How does Cialis work in the body?

The effectiveness of Tadalafil (the main component in Cialis) was assessed during many clinical studies involving men of different ages in whom ED was caused by a variety of factors. Naturally an erection occurs during sexual stimulation when nitric oxide is released. The blood flows into the penile area. The extra blood flow in the penis is caused by the relaxation of penile arteries and corpus cavernosal smooth muscle. The sexual response is induced by the synthesis of cGMP in smooth muscle cells. This substance causes smooth muscle relaxation. Tadalafil inhibits phosphodiesterase type 5 (PDE5).

PDE5 is known for its ability to diminish cGMP. When Cialis Soft inhibits PDE5, it creates conditions for normal erection occurrence. The medication enhances erectile function by increasing the amount of cGMP. Tadalafil works selectively for PDE5. Still it may have mild restricting properties for other PDEs.